Acinic cell carcinoma risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ramyar Ghandriz MD[2]
Overview
There is very little approved information about acinic cell carcinoma risk factors but Familial predisposition Previous radiation exposure may play an important role.
Risk Factors
There is very little known about acinic cell carcinoma risk factors, but the following features are established:[1][2][3]
- Familial predisposition
- Previous radiation exposure
- there were no cases among long-term atomic bomb survivors
- Cowden syndrome
- Acinic breast cancer may develop in a BRCA1 mutation carrier
References
- ↑ Saku T, Hayashi Y, Takahara O, Matsuura H, Tokunaga M, Tokunaga M; et al. (1997). "Salivary gland tumors among atomic bomb survivors, 1950-1987". Cancer. 79 (8): 1465–75. PMID 9118025.
- ↑ Depowski PL, Setzen G, Chui A, Koltai PJ, Dollar J, Ross JS (1999). "Familial occurrence of acinic cell carcinoma of the parotid gland". Arch Pathol Lab Med. 123 (11): 1118–20. doi:10.1043/0003-9985(1999)123<1118:FOOACC>2.0.CO;2. PMID 10539921.
- ↑ Villeneuve, Hugo; Tremblay, Steve; Galiatsatos, Polymnia; Hamel, Nancy; Guertin, Louis; Morency, Renald; Tischkowitz, Marc (2011). "Acinic cell carcinoma of the retromolar trigone region: expanding the tumor phenotype in Cowden syndrome?". Familial Cancer. 10 (4): 691–694. doi:10.1007/s10689-011-9472-8. ISSN 1389-9600.