Subependymal giant cell astrocytoma CT

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

Head CT scan may be helpful in the diagnosis of subependymal giant cell astrocytoma. On head CT scan, subependymal giant cell astrocytoma is characterized by an intraventricular mass near the foramen of Monro, which is iso- or slightly hypoattenuating to the grey matter. Accompanying hydrocephalus may be present. There is marked enhancement on contrast administration.[1]

CT

Head CT scan may be helpful in the diagnosis of subependymal giant cell astrocytoma. Findings on CT scan suggestive of/diagnostic of subependymal giant cell astrocytoma include:[2][3][4]

  • Round, heterogeneous mass
  • Uniform post-contrast enhancement
  • Cyst
  • Calcification
  • Iso- or slightly hypoattenuating to grey matter
  • Enlargement of the ventricles
  • Perilesional edema

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References

  1. Radiographic CT features of subependymal giant cell astrocytoma. Dr Bruno Di Muzio and Dr Jeremy Jones et al. Radiopaedia 2015. http://radiopaedia.org/articles/subependymal-giant-cell-astrocytoma. Accessed on November 4, 2015
  2. Jung TY, Kim YH, Jung S, Baek HJ, Lee KH (2015). "The clinical characteristics of subependymal giant cell astrocytoma: five cases". Brain Tumor Res Treat. 3 (1): 44–7. doi:10.14791/btrt.2015.3.1.44. PMC 4426277. PMID 25977907.
  3. Stein JR, Reidman DA (2016). "Imaging Manifestations of a Subependymal Giant Cell Astrocytoma in Tuberous Sclerosis". Case Rep Radiol. 2016: 3750450. doi:10.1155/2016/3750450. PMC 4752974. PMID 26942030.
  4. Moran V, O'Keeffe F (1986). "Giant cell astrocytoma in tuberous sclerosis: computed tomographic findings". Clin Radiol. 37 (6): 543–5. doi:10.1016/s0009-9260(86)80009-5. PMID 3791849.
  5. Image courtesy of Dr. Paresh K Desai. Radiopaedia (original file here). Creative Commons BY-SA-NC


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