Secondary amyloidosis laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2]

Overview

An elevated urinary protein is suggestive of secondary amyloidosis.

Laboratory Findings

• Laboratory findings suggestive of secondary amyloidosis vary depending on the affected organ.
• The most commonly observable finding is proteinuria, particularly nephrotic range (>3.5 g/day).
• Other possible laboratory findings include:
  • Elevated NT-proBNP in case of cardiac involvement.
  • Alkaline phosphatase Value >1.5 upper limit of normal in case of liver involvement.
  • Elevated level of acute phase reactant due to underlying inflammatory condition.