Beriberi MRI

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Abdelrahman Ibrahim Abushouk, MD[2]

Overview

In Wernicke-Korsakoff Syndrome patients, MRI may show some changes, including atrophy of mamillary bodies and hyperintense signals in the mesial dorsal thalami and periaqueductal grey matter.

MRI

In Wernicke-Korsakoff Syndrome patients, MRI may show the following changes :

• Atrophy of mamillary bodies.
• Hyperintense signals in the mesial dorsal thalami
• Hyperintense signals in the periaqueductal grey matter
• On T1 C+ MRI, contrast enhancement in the aforementioned regions.
• DWI/ADC: Restricted diffusion in the same regions.
• MR spectroscopy: Reduced N-acetylaspartic acid and increased lactate concentrations.

Selected FLAIR MRI images of the brain demonstrates hyperintensities in the periaqueductal region and the medial thalami. Case courtesy of A.Prof Frank Gaillard.

References

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