Hypertrophic cardiomyopathy
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Hypertrophic cardiomyopathy | |
Hypertrophic cardiomyopathy. Image courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Synonyms and keywords: Hypertrophic cardiomyopathy or HCM, Asymmetric septal hypertrophy or ASH, Hypertrophic obstructive cardiomyopathy, HOCM, Idiopathic hypertrophic subaortic stenosis or IHSS, familial isolated hypertrophic obstructive cardiomyopathy, familial isolated hypertrophic subaortic stenosis, familial or idiopathic hypertrophic subaortic stenosis, familial or idiopathic hypertrophic obstructive cardiomyopathy, primitive hypertrophic obstructive cardiomyopathy, primitive hypertrophic subaortic stenosis, muscular subaortic stenosis, apical hypertrophic cardiomyopathy, which is also known as nonobstructive hypertrophic cardiomyopathy and Japanese variant hypertrophic cardiomyopathy or the Yamaguchi variant (since the first cases described were all in individuals of Japanese descent)
Overview
Historical Perspective
Classification
Pathophysiology
Differentiating Hypertrophic Cardiomyopathy from other Diseases
Causes
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Study of Choice| History and Symptoms | Physical examination | Laboratory findings | Electrocardiogram | X Ray | Echocardiography and Ultrasound | CT Scan | MRI |Other Imaging Findings | Other Diagnostic Studies.
Treatment
- Medical therapy, Interventions, Surgery, Primary Prevention, Secondary Prevention, Cost Effectiveness of Therapy, Future or Investigational Therapy
Contraindicated medications
Idiopathic hypertrophic subaortic stenosis is considered an absolute contraindication to the use of the following medications:
Special Patient Populations
Asymptomatic Patients | Management During Childhood | Hypotension/Cardiovascular collapse | Pregnancy
2011 ACCF/AHA Guideline Recommendations
Diagnostic testing:
Electrocardiogram | Echocardiography | Stress Testing | Cardiac Magnetic Resonance | Cardiac CT | Positron Emission Tomography
Management:
- Asymptomatic patients: Asymptomatic patients
- Symptomatic patints: Pharmacologic Management
| Invasive Therapies | Alcohol septal ablation | Septal Myectomy | Pacing | Selection of Patients for ICDs | Selection of ICD-Device type | Selection of Patients for Heart Transplantation
- Special Clinical Scenarios: Patients With LV Systolic Dysfunction | Sudden cardiac death Risk Stratification | Participation in Competitive or Recreational Sports and Physical Activity | Management of Atrial Fibrillation | Pregnancy/Delivery | Concomitant Coronary Disease