Heart transplantation epidemiology and demographics
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Editor(s)-in-Chief: C. Michael Gibson, M.S., M.D.; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [1]
Overview
Epidemiology and Demographics
Reporting of transplant statistics to the Registry of the International Society for Heart and Lung Transplantation (ISHLT) is required in the US, but not other countries. According to The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-sixth adult heart transplantation report — 2019: [1]
Incidence
- The volume of heart transplants reported to the ISHLT Registry is significantly higher owing to increased donor availability.
- Between the 1980s-1990s there was a steady increase in the incidence of a heart transplant but the numbers have since stabilized because of the limited number of donors.
- According to the ISHLT, about 4,000 heart transplants occur annually and about 2,200 per year in the United States.
Indications
- The leading indications for transplant in adult recipients are
- non-ischemic dilated cardiomyopathy- 51%
- ischemic cardiomyopathy 32%
Case-fatality rate/Mortality rate
- Post-transplant survival has improved and the median survival after adult heart transplants performed between 2002 and 2009 is 12.5 years.
- Causes of death in the long term have not changed in recent years. Death due to acute graft rejection is highest in the first 30 days and infectious complications are the leading cause in the first year.
Age
- Median recipient age is 55 years
- Median donor age in Europe has increased to 45 years and remains relatively stable in North America at 28 years and other countries at 31 years.
Gender
- Data from the ISHLT shows that more males have received a cardiac transplant between 2009-2016. [2]
Region
- The International Society for Heart and Lung Transplantation (ISHLT) compiles the data of cardiac transplants and other involved statistics in the United States.
- Reporting of transplant statistics to the Registry of the International Society for Heart and Lung Transplantation (ISHLT) is required in the US, but not other countries.
References
- ↑ Khush KK, Cherikh WS, Chambers DC, Harhay MO, Hayes D, Hsich E; et al. (2019). "The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-sixth adult heart transplantation report - 2019; focus theme: Donor and recipient size match". J Heart Lung Transplant. 38 (10): 1056–1066. doi:10.1016/j.healun.2019.08.004. PMC 6816343 Check
|pmc=value (help). PMID 31548031. - ↑ Kim IC, Youn JC, Kobashigawa JA (2018). "The Past, Present and Future of Heart Transplantation". Korean Circ J. 48 (7): 565–590. doi:10.4070/kcj.2018.0189. PMC 6031715. PMID 29968430.