Asperger syndrome differential diagnosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
There are several differential diagnosis to consider in the diagnosis of Asperger Syndrome (AS).
Differential Diagnosis of Asperger Syndrome
- Conditions that must be considered in a differential diagnosis include:
- Autism spectrum disorder (ASD)[1][2]
- Attention deficit–hyperactivity disorder (ADHD)[1][2]
- Obsessive compulsive disorder (OCD)[1][2]
- Schizophrenia[1]
- Schizophrenia simplex[2]
- Residual schizophrenia[2]
- Schizoid personality disorder[1][2]
- Schizotypal personality disorder[1][2]
- Semantic pragmatic disorder[1]
- Nonverbal learning disorder[1][2]
- Mood disorders (depression and anxiety)[1][2]
- Stereotypic movement disorder[1]
- Alexithymia[2]
- Avoidant personality disorder[2]
- Antisocial personality disorder[2]
- Borderline personality disorder[2]
- Narcissistic personality disorder[2]
- Nonverbal learning disorder[2]
- Post traumatic stress disorder (PTSD)[2]
- Social phobia[2]
- Compulsive (anankastic) personality disorder
- The following table shows the overlap of some differential diagnoses of AS that have abnormal social interaction:[2]
| Some Differential Diagnosis of Asperger Syndrome
(Modified Table from The Investigation and Differential Diagnosis of Asperger Syndrome in Adults)[2] | ||||||||
| Asperger Syndrome | Schizoid Personality Disorder | Schizotypal Personality Disorder | Avoidant Personality Disorder | Social Phobia | Obsessive Personality Disorder | Obsessive-compulsive disorder (OCD) | Attention deficit–hyperactivity disorder (ADHD) | |
| Abnormal social interaction | + | + | + | + | + | + | + | + |
| Abnormal verbal communication | + | + | + | - | - | - | - | - |
| Abnormal facial expression/gestures/prosody | + | + | + | + | +/- | - | - | +/- |
| Abnormal eye contact | + | + | +/- | + | +/- | - | - | +/- |
| Abnormal theory of mind | + | +/- | +/- | +/- | +/- | +/- | - | +/- |
| Abnormal empathy | + | +/- | +/- | - | - | +/- | - | +/- |
| Abnormal interests/rituals/compulsions | + | +/- | +/- | - | - | + | + | - |
| Abnormal attention | +/- | - | - | - | - | - | - | + |
| Abnormal psychomotor function | + | - | +/- | - | - | - | - | +/- |
| Abnormal self-injurious behavior | +/- | +/- | +/- | - | - | - | - | +/- |
| Abnormal psychotic manifestations | +/- | - | +/- | - | - | - | - | - |
| Abnormal social interaction in childhood | + | +/- | +/- | +/- | - | - | - | + |
| Abnormal biographical stress factors | - | + | +/- | + | +/- | + | +/- | +/- |
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 Fitzgerald, Michael; Corvin, Aiden (2018). "Diagnosis and differential diagnosis of Asperger syndrome". Advances in Psychiatric Treatment. 7 (4): 310–318. doi:10.1192/apt.7.4.310. ISSN 1355-5146.
- ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 2.13 2.14 2.15 2.16 2.17 2.18 Lehnhardt FG, Gawronski A, Pfeiffer K, Kockler H, Schilbach L, Vogeley K (2013). "The investigation and differential diagnosis of Asperger syndrome in adults". Dtsch Arztebl Int. 110 (45): 755–63. doi:10.3238/arztebl.2013.0755. PMC 3849991. PMID 24290364.