Heartburn risk factors
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Common Heartburn Risk Factors
- Common risk factors in the development of heartburn is obesity, increasing age, smoking, hiatal hernia, white bread, chocolate, mint, cinnamon, carbonated beverages, fatty foods, alcohol, wine and beer.
- Exercising and coffee intake were considered protective factors.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107529/
- Women experience heartburn generally 5 years later than men. https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/485088
Risk Factors: |
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Obesity |
Age |
Smoking |
Hiatal Hernia |
Dietary Risk Factors |
White bread |
Chocolate |
Mint |
Cinnamon |
Carbonated beverages |
Fatty foods |
Alcohol - Wine and ber |
Genetic Risk Factors |
C allele in FOX1 rs9936833 - ↑ reflux symptoms |
A allele in MHC rs9257809 - ↑ reflux symptoms |
rs10419226 (chr 19) - ↑GERD symptoms |
rs2687201 (chr 3) ↑GERD symptoms |
ABHD10, RNF7, RASGRF2, BTF3P7, C8orf4, GLDC, and ADAMTS17 |