Pneumoconiosis natural history, complications and prognosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dushka Riaz, MD
Overview
If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
OR
Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].
OR
Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
Natural History, Complications, and Prognosis
Natural History
- The symptoms of pneumoconiosis typically develop ___ years after exposure to ___.
- If left untreated, [#]% of patients with pneumconiosis may progress to develop pulmonary fibrosis and respiratory failure.
Complications
- Common complications of pneumoconiosis include: [1] [2] [3]
- Pulmonary fibrosis
- Emphysema
- COPD
- Pleural effusion
- Pleural plaques
- Malignant Mesothelioma (Asbestosis)
- Carcinoma
- Tuberculosis
- Scleroderma
- SLE
- Glomerulonephritis
- Pulmonary hypertension
- Cor pulmonale
- Respiratory failure
Prognosis
The prognosis for pneumoconiosis is poor and leads to respiratory complications and premature death. The prognosis is deemed to be poor particularly when fibrosis is found on CT scans. [4] [5] [6] Patients progress quickly to cor pulmonale and respiratory failure. In the case of silicosis, the survival is generally less than four years. [7] [8]
References
- ↑ Fujimura N (2000). "Pathology and pathophysiology of pneumoconiosis". Curr Opin Pulm Med. 6 (2): 140–4. doi:10.1097/00063198-200003000-00010. PMID 10741774.
- ↑ Chong S, Lee KS, Chung MJ, Han J, Kwon OJ, Kim TS (2006). "Pneumoconiosis: comparison of imaging and pathologic findings". Radiographics. 26 (1): 59–77. doi:10.1148/rg.261055070. PMID 16418244.
- ↑ Cullinan P, Reid P (2013). "Pneumoconiosis". Prim Care Respir J. 22 (2): 249–52. doi:10.4104/pcrj.2013.00055. PMC 6442808. PMID 23708110.
- ↑ "StatPearls". 2021. PMID 32310362 Check
|pmid=value (help). - ↑ Sahin H, Brown KK, Curran-Everett D, Hale V, Cool CD, Vourlekis JS; et al. (2007). "Chronic hypersensitivity pneumonitis: CT features comparison with pathologic evidence of fibrosis and survival". Radiology. 244 (2): 591–8. doi:10.1148/radiol.2442060640. PMID 17641377.
- ↑ Walsh SL, Sverzellati N, Devaraj A, Wells AU, Hansell DM (2012). "Chronic hypersensitivity pneumonitis: high resolution computed tomography patterns and pulmonary function indices as prognostic determinants". Eur Radiol. 22 (8): 1672–9. doi:10.1007/s00330-012-2427-0. PMID 22466512.
- ↑ Marchiori E, Ferreira A, Müller NL (2001). "Silicoproteinosis: high-resolution CT and histologic findings". J Thorac Imaging. 16 (2): 127–9. doi:10.1097/00005382-200104000-00012. PMID 11292205.
- ↑ Marchiori E, Souza CA, Barbassa TG, Escuissato DL, Gasparetto EL, Souza AS (2007). "Silicoproteinosis: high-resolution CT findings in 13 patients". AJR Am J Roentgenol. 189 (6): 1402–6. doi:10.2214/AJR.07.2402. PMID 18029877.