Chorioamnionitis natural history, complications and prognosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Adnan Ezici, M.D[2]
Overview
Clinical findings associated with chorioamnionitis include maternal fever, uterine tenderness, purulent/foul-smelling amniotic fluid, maternal/fetal tachycardia. Common fetal complications of chorioamnionitis include preterm birth, neonatal sepsis, neurologic complications, respiratory complications. Common maternal complications of chorioamnionitis include maternal sepsis, infections, and labor-related complications (e.g., cesarean section, postpartum hemorrhage, etc.)
Natural History, Complications, and Prognosis
Natural History
The symptoms of chorioamnionitis usually develop during the pregnancy, and start with symptoms such as maternal fever, uterine tenderness, purulent/foul-smelling amniotic fluid, maternal/fetal tachycardia.[1]
Complications
Fetal complications that can develop as a result of chorioamnionitis are:[2][3]
- Preterm birth
- Retinopathy of prematurity
- Neonatal sepsis
- Neonatal death
- Neurologic complications
- Respiratory complications
Maternal complications that can develop as a result of chorioamnionitis are:[3][1]
- Maternal sepsis
- Infections
- Severe pelvic infections and abscess
- Wound infections
- Endomyometritis
- Labor-related complications
Prognosis
The presence of cesarean delivery for dystocia, prolonged labor times (≥ 10 h), or administration of oxytocin during labor are associated with a particularly poor prognosis among infants exposed to chorioamnionitis.[4]
References
- ↑ 1.0 1.1 Tita AT, Andrews WW (June 2010). "Diagnosis and management of clinical chorioamnionitis". Clin Perinatol. 37 (2): 339–54. doi:10.1016/j.clp.2010.02.003. PMC 3008318. PMID 20569811.
- ↑ Ericson JE, Laughon MM (March 2015). "Chorioamnionitis: implications for the neonate". Clin Perinatol. 42 (1): 155–65, ix. doi:10.1016/j.clp.2014.10.011. PMC 4331454. PMID 25678002.
- ↑ 3.0 3.1 Fowler JR, Simon LV. PMID 30335284. Missing or empty
|title=(help) - ↑ Alexander JM, McIntire DM, Leveno KJ (August 1999). "Chorioamnionitis and the prognosis for term infants". Obstet Gynecol. 94 (2): 274–8. doi:10.1016/s0029-7844(99)00256-2. PMID 10432142.