Acute disseminated encephalomyelitis overview

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Acute disseminated encephalomyelitis Microchapters

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Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Acute disseminated encephalomyelitis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

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CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

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Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]: Associate Editor(s)-in-Chief:

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Overview

Acute disseminated encephalomyelitis (ADEM) is an acute neurologic disease of the central nervous system characterized by scattered foci of demyelination and perivenular inflammation. The disease may occur without precipitant, or may develop after infection or vaccination.

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Acute disseminated encephalomyelitis from Other Diseases

No one test established the diagnosis of ADEM. Supporting features include an appropriate viral or vaccination history, an appropriate acute neurologic illness, and consistent features on CNS imaging.

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications, and Prognosis

Diagnosis

Diagnostic Study of Choice

There is no single diagnostic study of choice for the diagnosis of acute disseminated encephalomyelitis.

History and Symptoms

Physical Examination

Laboratory Findings

Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Prevention

References

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