Eczema causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-in-Chief: Edzel Lorraine Co, D.M.D., M.D.
Overview
Eczema could be due to a genetic problem, or a result of the adverse effect of certain medication.
Causes
- Damage from the enzymatic activity of allergens is usually prevented by the body's own protease inhibitors, such as, LEKTI, produced from the gene SPINK5.
- Lack of filaggrin gene causes dry skin. [1]
Common Medications with Eczema as the Adverse Drug Effect
- Below is a list of commonly prescribed medications with eczema as the common adverse drug effect (Table 1).
Medication |
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Cidofovir |
Flurbiprofen |
Olaparib |
Siltuximab |
Sorafenib |
Tiagabine |
References
- ↑ Palmer CN, Irvine AD, Terron-Kwiatkowski A, Zhao Y, Liao H, Lee SP; et al. (2006). "Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis". Nat Genet. 38 (4): 441–6. doi:10.1038/ng1767. PMID 16550169.