Rheumatic fever primary prevention
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Lance Christiansen, D.O.; Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2]
Prevention
Agent | Children ≤ 27 kg (60 lb) | Adolescents and Adults > 27 kg (60 lb) | Mode | Duration | Rating |
---|---|---|---|---|---|
Penicillin Therapy | |||||
Penicillin V (phenoxymethyl penicillin) | 250 mg 2 to 3 times daily | 500 mg 2 to 3 times daily | Oral | 10 days | Class I, LOE B |
or | |||||
Amoxicillin | 50 mg/kg once daily (maximum 1 g) | 50 mg/kg once daily (maximum 1 g) | Oral | 10 days | Class I, LOE B |
or | |||||
Benzathine penicillin G | 600,000 U | 1,200,000 U | Intramuscular | Once | Class I, LOE B |
References
- ↑ Gerber MA, Baltimore RS, Eaton CB, Gewitz M, Rowley AH, Shulman ST; et al. (2009). "Prevention of rheumatic fever and diagnosis and treatment of acute Streptococcal pharyngitis: a scientific statement from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young, the Interdisciplinary Council on Functional Genomics and Translational Biology, and the Interdisciplinary Council on Quality of Care and Outcomes Research: endorsed by the American Academy of Pediatrics". Circulation. 119 (11): 1541–51. doi:10.1161/CIRCULATIONAHA.109.191959. PMID 19246689.