Spontaneous bacterial peritonitis secondary prevention

	Peritonitis main page
	Spontaneous bacterial peritonitis Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Spontaneous bacterial peritonitis from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
History & Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
Chest X Ray
CT
MRI
Echocardiography or Ultrasound
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Spontaneous bacterial peritonitis secondary prevention On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Spontaneous bacterial peritonitis secondary prevention All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Spontaneous bacterial peritonitis secondary prevention
CDC on Spontaneous bacterial peritonitis secondary prevention
Spontaneous bacterial peritonitis secondary prevention in the news
Blogs on Spontaneous bacterial peritonitis secondary prevention
Directions to Hospitals Treating Spontaneous bacterial peritonitis
Risk calculators and risk factors for Spontaneous bacterial peritonitis secondary prevention

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

All patients who have survived an episode of SBP should receive long-term prophylaxis with daily norfloxacin (or trimethoprim/sulfamethoxazole) because this is the most data-supported indication for long-term outpatient prophylaxis. ^[1]

All cirrhotic patients might benefit from antibiotics if:
- Ascitic fluid protein <1.0 g/dL^[2]. Patients with fluid protein <15 g/L and either Child-Pugh score of at least 9 or impaired renal function may also benefit.

↑ http://guideline.gov/content.aspx?id=14887&search=ascitis
↑ Runyon BA (1986). "Low-protein-concentration ascitic fluid is predisposed to spontaneous bacterial peritonitis". Gastroenterology. 91 (6): 1343–6. PMID 3770358.
↑ Grangé JD, Roulot D, Pelletier G; et al. (1998). "Norfloxacin primary prophylaxis of bacterial infections in cirrhotic patients with ascites: a double-blind randomized trial". J. Hepatol. 29 (3): 430–6. PMID 9764990.