Guillain-Barré syndrome laboratory tests
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editors-In-Chief: Priyamvada Singh, MBBS [2]
Overview
Guillain-Barré syndrome (GBS) is usually diagnosed clinically. Lab tests are done to exclude other diagnosis and assess prognosis. The lab tests ordered are basic labs (CBC, ESR), lumbar puncture (GBS has characteristic albuminocytological dissociation), serological markers
Laboratory test
A panel of tests can be ordered in cases of diagnostic uncertainty with other peripheral neuropathies
- Vitamin B 12, folic acid
- Thyroid profile (to rule out thyroid neuropathies)
- ESR (Erythrocyte sedimentation rate) increased in inflammatory process
- Rheumatology profiles
- Hemoglobin A1c for diabetic neuropathy
- Immunoelectrophoresis for serum protein (multiple myeloma)
- Heavy metal poisoning