Amnesia pathophysiology
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief:Aditya Govindavarjhulla, M.B.B.S. [2]
Overview
Amnesia results from damage to different memory centers in the brain which are involved in acquiring and restoring memory.
Pathophysiology
The memory is affected by the damage that may occur in the different parts of the brain such as medial temporal lobe, hippocampus, cortex and frontal lobes. Injuring any of these areas may lead to specific disruptions in the processes of acquiring and restoring memory. For instance, damage to the medial temporal lobe and hippocampus can devastate the ability to acquire new declarative memory whereas damage to the storage areas in cortex can disrupt retrieval of old memories and interfere with acquisition of new memories.[1]