Dermatan sulfate

WikiDoc Resources for Dermatan sulfate
Articles
Most recent articles on Dermatan sulfate Most cited articles on Dermatan sulfate Review articles on Dermatan sulfate Articles on Dermatan sulfate in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Dermatan sulfate Images of Dermatan sulfate Photos of Dermatan sulfate Podcasts & MP3s on Dermatan sulfate Videos on Dermatan sulfate
Evidence Based Medicine
Cochrane Collaboration on Dermatan sulfate Bandolier on Dermatan sulfate TRIP on Dermatan sulfate
Clinical Trials
Ongoing Trials on Dermatan sulfate at Clinical Trials.gov Trial results on Dermatan sulfate Clinical Trials on Dermatan sulfate at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Dermatan sulfate NICE Guidance on Dermatan sulfate NHS PRODIGY Guidance FDA on Dermatan sulfate CDC on Dermatan sulfate
Books
Books on Dermatan sulfate
News
Dermatan sulfate in the news Be alerted to news on Dermatan sulfate News trends on Dermatan sulfate
Commentary
Blogs on Dermatan sulfate
Definitions
Definitions of Dermatan sulfate
Patient Resources / Community
Patient resources on Dermatan sulfate Discussion groups on Dermatan sulfate Patient Handouts on Dermatan sulfate Directions to Hospitals Treating Dermatan sulfate Risk calculators and risk factors for Dermatan sulfate
Healthcare Provider Resources
Symptoms of Dermatan sulfate Causes & Risk Factors for Dermatan sulfate Diagnostic studies for Dermatan sulfate Treatment of Dermatan sulfate
Continuing Medical Education (CME)
CME Programs on Dermatan sulfate
International
Dermatan sulfate en Espanol Dermatan sulfate en Francais
Business
Dermatan sulfate in the Marketplace Patents on Dermatan sulfate
Experimental / Informatics
List of terms related to Dermatan sulfate

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

==Overview==Dermatan sulfate is a glycosaminoglycan (formerly called a mucopolysaccharide) found mostly in skin, but also in blood vessels, heart valves, tendons, and lungs.

It is also referred to as chondroitin sulfate B, although it is no longer classified as a form of chondroitin sulfate by most sources.

Function

Dermatan sulfate may have roles in coagulation, cardiovascular disease, carcinogenesis, infection, wound repair, and fibrosis.

Pathology

Dermatan sulfate accumulates abnormally in several of the mucopolysaccharidosis disorders.

An excess of Dermatan Sulfate in the Mitral Valve is characteristic of myxomatous degeneration of the leaflets leading to redundancy of valve tissue and ultimately, Mitral Valve Prolapse (into the Left Ventricle) and insufficiency. This chronic prolapse occurs mainly in women over the age of 60, and can predispose the patient to mitral annular calcification and eccentric (volume dependent or dilated) hypertrophy and eventually Left Heart failure if untreated. Also used to treat sun burns.

See also

• iduronic acid

External links

• B01AX04 (WHO)
• Dermatan+sulfate at the US National Library of Medicine Medical Subject Headings (MeSH)