Transposition of the great vessels anatomy
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.B.B.S. [2]; Cafer Zorkun, M.D., Ph.D. [3]; Keri Shafer, M.D. [4]; Assistant Editor(s)-In-Chief: Kristin Feeney, B.S. [5]
Overview
Anatomy
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Normal Heart
- Normally, the morphologic right atrium (RA) is connected to a morphologic right ventricle (RV). The morphologic left atrium (LA) is connected to the morphologic left ventricle (LV). This is called atrio-ventricular concordance.
- In a normal heart, the great arteries (aorta and pulmonary arteries) are concordant with the morphologic LV and RV. This is termed ventriculo-arterial concordance.
- In addition, the aorta and pulmonary trunk ascend in a spiral relationship.
Transposition of the great vessels
- In the TGA the aorta arises from the morphologic right ventricle via a subaortic infundibulum and the pulmonary artery arises from the morphologic left ventricle, without a subpulmonary infundibulum. These ventriculoarterial connection is known as ventriculoarterial discordance. As a consequence, there is a a fibrous continuity between the mitral and pulmonary valve, but no continuity between the tricuspid and aortic valve.
- The abnormal origin of the great arteries results in an altered spiral relationship. Therefore, the aorta and pulmonary artery run parallel to each other
- In normal heart thus the circulation is in series. However, in transposition of the great vessels circulation is in parallel
dextro-Transposition of the great vessels
- d-TGA is also referred to as complete or uncorrected transposition of the great arteries identifying the single discordance between ventricles and great arteries
levo-Transposition of the great vessels
- l-TGA is referred to as congenitally corrected transposition, identifying a double discordance (atrioventricular and ventriculoarterial).