Transposition of the great vessels epidemiology and demographics

Transposition of the great vessels Microchapters
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Dextro-transposition of the great arteries
L-transposition of the great arteries
Pathophysiology
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Epidemiology and Demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.B.B.S. [2]; Cafer Zorkun, M.D., Ph.D. [3]; Keri Shafer, M.D. [4]; Assistant Editor(s)-In-Chief: Kristin Feeney, B.S. [5]

Overview

Transposition of the great arteries most commonly present within first 24 hours of life

Epidemiology and Demographics

Incidence

• Transposition of the great arteries TGA is one of the commonest cyanotic congenital heart defects present in the first 24 hours of life.
• An incidence at birth of 20-30 in 100000 live births
• TGA represents 5-7% of all CHD.
• Almost 20 percent of all cyanotic CHD defects
• TGA is more common in infants of diabetic mothers.

Gender

• Boys outnumber girls with an approximate ratio of 2:1.
• Without treatment, 30% of infants die within the first week of life, 50% will die in the first month, 70% will die in the first 6 months and 90% of infants will die before the end of the first year.