Aortic stenosis epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Mohammed A. Sbeih, M.D. [2]; Lakshmi Gopalakrishnan, M.B.B.S. [3]; Assistant Editor-In-Chief: Kristin Feeney, B.S. [4]

Overview

Aortic stenosis is a major health problem primarily affecting older adults and majority is due to calcific degeneration. Aortic stenosis tends to affect approximately 2% of patients over the age of 65, 3% the age of 75, and 4% over the age 85.[1]

Epidemiology and Demographics

Based on the results from the EuroHeart Failure survey programme, 4.8% of patients with acute coronary syndrome enrolled had significant valve disease, in particular ischemic mitral regurgitation and calcific aortic stenosis[2] and were associated with poor prognosis.[3]

Age

The prevalence of aortic stenosis increases with age. Less than 1% of all live births exhibit symptoms of severe aortic stenosis. Approximately 2% of patients over the age of 65, 3% over the age of 75, and 4% over the age of 85 have aortic stenosis.[1] The Helsinki Ageing study evaluated 552 patients with aortic valve disease, of which 53% were reported to have calcified aortic valves and the prevalence of critical aortic valve stenosis (aortic valve area = less than 1.2 cm2) was observed to be 2.9% among the 75 to 86 years age group.[4]

Gender

Calcific degenerative aortic stenosis is more common in males [5].

Developed Countries

In North America and Europe, a linear relationship exists between an aging population and an increase in the incidence of aortic stenosis.

References

  1. 1.0 1.1 Stewart BF, Siscovick D, Lind BK, Gardin JM, Gottdiener JS, Smith VE, Kitzman DW, Otto CM (1997). "Clinical factors associated with calcific aortic valve disease. Cardiovascular Health Study". Journal of the American College of Cardiology. 29 (3): 630–4. PMID 9060903. Retrieved 2012-04-11. Unknown parameter |month= ignored (help)
  2. Cleland JG, Swedberg K, Follath F, Komajda M, Cohen-Solal A, Aguilar JC, Dietz R, Gavazzi A, Hobbs R, Korewicki J, Madeira HC, Moiseyev VS, Preda I, van Gilst WH, Widimsky J, Freemantle N, Eastaugh J, Mason J (2003). "The EuroHeart Failure survey programme-- a survey on the quality of care among patients with heart failure in Europe. Part 1: patient characteristics and diagnosis". European Heart Journal. 24 (5): 442–63. PMID 12633546. Retrieved 2012-04-11. Unknown parameter |month= ignored (help)
  3. Hasdai D, Lev EI, Behar S, Boyko V, Danchin N, Vahanian A, Battler A (2003). "Acute coronary syndromes in patients with pre-existing moderate to severe valvular disease of the heart: lessons from the Euro-Heart Survey of acute coronary syndromes". European Heart Journal. 24 (7): 623–9. PMID 12657220. Retrieved 2012-04-11. Unknown parameter |month= ignored (help)
  4. Lindroos M, Kupari M, Heikkilä J, Tilvis R (1993). "Prevalence of aortic valve abnormalities in the elderly: an echocardiographic study of a random population sample". Journal of the American College of Cardiology. 21 (5): 1220–5. PMID 8459080. Retrieved 2012-04-11. Unknown parameter |month= ignored (help)
  5. Townsend CM, et al. Sabiston Textbook of Surgery. 18th ed. Saunders; 2008:1841-1844.


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