Aspergillosis natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]

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Overview

With treatment, people with allergic aspergillosis usually gets better over time. Relapse is common and needs repeated treatment. It could be fatal if un-responsive to treatment. Prognosis also depends on the patients immune status.

Complications

• Amphotericin B can cause kidney damage and unpleasant side effects such as fever and chills
• Bronchiectasis (permanent scarring and enlargement of the small sacs in the lungs)
• Invasive lung disease can cause massive bleeding from the lung
• Mucus plugs in the airways
• Permanent airway blockage