Lactic acidosis classification
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Classification
The Cohen-Woods classification (1976) categorises causes of lactic acidosis as follows:
- Type A: Decreased perfusion or oxygenation
- Type B:
- B1: Underlying diseases (sometimes causing type A)
- B2: Medication or intoxication
- B3: Inborn error of metabolism
Lactic acidosis is an underlying process in the development of rigor mortis. Tissue in the muscles of the deceased resort to anaerobic metabolism in the absence of oxygen and significant amounts of lactic acid are released into the muscle tissue. This along with the loss of ATP causes the muscles to grow stiff.