Guillain-Barré syndrome diagnostic criteria

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Priyamvada Singh, MBBS [2]

Overview

Diagnostic Criteria

Required

  • Progressive, relatively symmetrical weakness of 2 or more limbs due to neuropathy
  • Areflexia
  • Disease course < 4 weeks
  • Exclusion of other causes (see below)

Supportive

  • Relatively symmetric weakness accompanied by numbness and/or tingling
  • Mild sensory involvement
  • Facial nerve or other cranial nerve involvement
  • Absence of fever
  • Typical CSF findings obtained from lumbar puncture
  • Electrophysiologic evidence of demyelination from electromyogram

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