Severe acute respiratory syndrome
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Synonyms and keywords: SARS; SARS associated
Overview
Historical Perspective
Pathophysiology
Differentiating Severe Acute Respiratory Syndrome from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Criteria | History and Symptoms | Physical Examination | Laboratory Findings | Chest X Ray | Other Imaging Findings | Other Diagnostic Studies
Treatment
Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies | Social Impact
- Preferred regimen: supportive therapy
- Note: New therapies were studied for SARS during the last outbreaks which concluded
- Ribavirin ineffective and probably harmful due to haemolytic anaemia.
- Lopinavir AND Ritonavir is still controversial and need further investigation.
- Interferon has no benefit and its studies are inconclusive.
- Corticosteroids increases risk of fungal infections, some studies showed a higher incidence of psychosis, diabetes, avascular necrosis and osteoporosis.
- Inhaled Nitric oxide potent mediator of airway inflammation, its has improved oxygenation in some studies.
Case Studies
External Links
- Official SARS information from the World Health Organization
- Official SARS information from the United States Centers for Disease Control
- NIOSH Topic Area: Severe Acute Respiratory Syndrome (SARS)
- NIOSH Publication: Understanding Respiratory Protection Against SARS
Template:Baltimore classification Template:Viral diseases
Template:Respiratory pathology
- ↑ Gilbert, David (2014). The Sanford guide to antimicrobial therapy 2014. Sperryville, Va: Antimicrobial Therapy. ISBN 978-1930808782.
- ↑ Stockman LJ, Bellamy R, Garner P (2006). "SARS: systematic review of treatment effects". PLoS Med. 3 (9): e343. doi:10.1371/journal.pmed.0030343. PMC 1564166. PMID 16968120.
- ↑ Groneberg DA, Poutanen SM, Low DE, Lode H, Welte T, Zabel P (2005). "Treatment and vaccines for severe acute respiratory syndrome". Lancet Infect Dis. 5 (3): 147–55. doi:10.1016/S1473-3099(05)01307-1. PMID 15766649.