Pulseless electrical activity risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
The administration of beta blockers and calcium channel blockers is associated with an increased risk of PEA. This may be due to their effect on Ca / troponin interactions, and their inhibition of myocardial contractility. History of syncope and pulmonary disease is also associated with a higher risk of presenting PEA [1], as well as history of syncope.
Risk Factors
=Beta Blockers and Calcium Channel Blockers
Syncope and PEA
There is a strong correlation between patients that had a syncope episode to present future PEA, than those who didn’t. Prevalence is also higher in patients that presented PEA, than those who presented VF/VT or asystolia. Findings were consistent with an odds ratio of 2.64 (Confidence interval 1.31 to 5.32) versus VF/VT and OR of 2.27 (Confidence interval of 1.08 to 4.78) versus asystolia [1].
Pulmonary Disease and PEA
Teodorescu et al suggest, a strong relation between pulmonary disease and increased frequency of PEA. There are other publications supporting this association [2] [3].
References
- ↑ 1.0 1.1 Teodorescu C, Reinier K, Dervan C, Uy-Evanado A, Samara M, Mariani R; et al. (2010). "Factors associated with pulseless electric activity versus ventricular fibrillation: the Oregon sudden unexpected death study". Circulation. 122 (21): 2116–22. doi:10.1161/CIRCULATIONAHA.110.966333. PMID 21060069.
- ↑ Pirolo JS, Hutchins GM, Moore GW (1985). "Electromechanical dissociation: pathologic explanations in 50 patients". Hum Pathol. 16 (5): 485–7. PMID 3988275.
- ↑ Herlitz J, Rosenfelt M, Bång A, Axelsson A, Ekström L, Wennerblom B; et al. (1996). "Prognosis among patients with out-of-hospital cardiac arrest judged as being caused by deterioration of obstructive pulmonary disease". Resuscitation. 32 (3): 177–84. PMID 8923578.