Idiopathic interstitial pneumonia overview
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Idiopathic Interstitial Pneumonia Microchapters |
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Differentiating Idiopathic interstitial pneumonia from other Diseases |
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Diagnosis |
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Treatment |
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Idiopathic interstitial pneumonia overview On the Web |
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Risk calculators and risk factors for Idiopathic interstitial pneumonia overview |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [2]
Overview
The idiopathic interstitial pneumonias (IIP) are a broad range of interstitial lung diseases of unknown etiology characterized by expansion of the interstitial compartment initially by inflammatory cells ending by fibrosis due to fibroblasts proliferation and subsequent collagen deposition. It generally manifests non specifically as breathlessness and cough and characterized by bilateral abnormal opacities of various types on conventional chest radiographs or computed tomographic (CT) scans. The prognosis of IIP differs according to the clinical course and pattern of the disease. The most common is chronic idiopathic pulmonary fibrosis, however the worst prognosis is the acute interstitial pneumonia (AIP). The diagnosis can only be reached correctly with multidisciplinary approach among different specialists after excluding a lot of known factors that could cause the same presentations. Unfortunately most of the available treatments till today did not show any survival benefit or reducing the mortality.