Cefpirome drug interactions

Cefpirome
CEFROM® Package Insert
Composition
Properties
Indications
Microbiology
Contraindications
Warnings and Precautions
Adverse Reactions
Drug Interactions
Dosage and Administration
How Supplied

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Drug Interactions

As with other cephalosporin antibiotics, Cefrom may potentiate the nephrotoxic effects of nephrotoxic drugs.

Laboratory invesligations: A positive Coombs test may occur in rare cases during treatment with cefpirome. Glycosuria must be measured by enzymatic methods during treatment, given that non-enzymatic techniques may produce a false positive reaction. Cefpirome may produce falsely raised serum creatinine values in the picrate assay. For this reason the use of an enzymatic method is recommended. If an enzymatic method is not available, the blood sample must be taken when the cefpirome serum levels are: considered to be below the limit of significant interference, i.e. immediately before administration of cefpirome or not earlier than 6 hours after administration.