Esophageal cancer classification
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Classification
Esophageal cancers are typically carcinomas, which arise from the epithelium, or surface lining of the esophagus. Most esophageal cancer fall into one of two classes: squamous cell carcinomas, which are similar to head and neck cancer in their appearance and association with tobacco and alcohol consumption, and adenocarcinomas, which are often associated with a history of gastroesophageal reflux disease and Barrett's esophagus.The adenocarcinomas of esophagus present clinically as that of gastric adenocarcinomas and make up more than 70% of esophageal cancers.
References
Enzinger PC, Mayer RJ: Esophageal cancer. N Engl J Med 349:2241, 2003[PMID: 14657432]