Creutzfeldt-Jakob disease other imaging findings

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Overview

CT scan mainly helps in excluding an alternative diagnosis and is generally normal in CJD.

CT Scan

Rapidly progressive ventricular enlargement and cortical atrophy have been shown to be present in CJD on serial CT scans.[1]

PET Scan

Abnormalities in thalamic region have been shown to be present on PET scan in thalamic MM2 subtype of CJD, however, its significance in diagnosis has not been extablished yet.[2][3]


References

  1. Hayashi, R.; Hanyu, N.; Kuwabara, T.; Moriyama, S. (1992). "Serial computed tomographic and electroencephalographic studies in Creutzfeldt-Jakob disease". Acta Neurol Scand. 85 (3): 161–5. PMID 1574996. Unknown parameter |month= ignored (help)
  2. Hamaguchi, T.; Kitamoto, T.; Sato, T.; Mizusawa, H.; Nakamura, Y.; Noguchi, M.; Furukawa, Y.; Ishida, C.; Kuji, I. (2005). "Clinical diagnosis of MM2-type sporadic Creutzfeldt-Jakob disease". Neurology. 64 (4): 643–8. doi:10.1212/01.WNL.0000151847.57956.FA. PMID 15728285. Unknown parameter |month= ignored (help)
  3. Macfarlane, RG.; Wroe, SJ.; Collinge, J.; Yousry, TA.; Jäger, HR. (2007). "Neuroimaging findings in human prion disease". J Neurol Neurosurg Psychiatry. 78 (7): 664–70. doi:10.1136/jnnp.2006.094821. PMID 17135459. Unknown parameter |month= ignored (help)


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