Ebola laboratory tests

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Michael Maddaleni, B.S.; Guillermo Rodriguez Nava, M.D. [2]

Overview

Ebola infection is associated with nonspecific laboratory abnormalities including alterations in the white blood cell count, blood chemistry tests and liver function tests, all of which may contribute to a disruption in the clotting process and bleeding.

Laboratory Findings

The table below displays the nonspecific laboratory abnormalities associated with Ebola infection, including:[1]

Laboratory findings
Test Findings
White blood cell count Leucopenia
Lymphopenia
Neutrophilia
Blood smear Left shift
Atypical lymphocytes
Coagulation Consumption of clotting factors
Increased concentrations of fibrin degradation products
Liver function tests Raised aspartate aminotransferase
Raised alanine aminotransferase
Extended prothrombin time
Extended partial thromboplastin time
Proteins Hyperproteinemia
Urinalysis Proteinuria

References

  1. Feldmann H, Geisbert TW (2011). "Ebola haemorrhagic fever". Lancet. 377 (9768): 849–62. doi:10.1016/S0140-6736(10)60667-8. PMC 3406178. PMID 21084112.

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