Group B streptococcal infection screening
Group B Streptococcal Infection Microchapters |
Differentiating Group B Streptococcal Infection from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rim Halaby, M.D. [2]
Overview
Screening
Indications
Culture- Versus Risk-Based Screening
Early guidelines recommended the use of one of two approaches to identifying women who should receive intrapartum antibiotic prophylaxis: a risk-based approach or a culture-based screening approach (13).
Providers using the risk-based method identified candidates for intrapartum chemoprophylaxis according to the presence of any of the following intrapartum risk factors: delivery at <37 weeks' gestation, intrapartum temperature ≥100.4ºF (≥38.0ºC), or rupture of membranes for ≥18 hours.
Providers using the culture-based screening method screened all pregnant women for vaginal and rectal GBS colonization between 35 and 37 week's gestation.
A large population-based study conducted during 1998--1999 demonstrated the superiority of culture-based screening over the risk-based approach to prevention of early-onset GBS disease (62). The study found that culture-based screening resulted in the identification of a greater proportion of women at risk for transmitting GBS to their newborns.