Group B streptococcal infection medical therapy

Group B Streptococcal Infection Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rim Halaby, M.D. [2]

Medical Therapy

Empirical Antibiotic Therapy in Neonatal Meningitis

GBS should be suspected as a causative agent for bacterial meningitis in infants less than two years of age for whom empirical antibiotic therapy should be initiated immediately.

Age	Possible pathogens causing the bacterial meningitis	Empirical treatment
< 1 month	Streptococcus agalactiae Escherichia coli Listeria monocytogenes Klebsiella	Ampicillin + cefotaxime OR Ampicillin + aminoglycoside
1-23 months	Streptococcus pneumoniae Neisseria meningitidis Streptococcus agalactiae Haemophilus influenzae E. coli	Vancomycin + third generation cephalosporin

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