Group B streptococcal infection laboratory tests
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rim Halaby, M.D. [2]
Overview
Laboratory Tests
Shown below is a tables that summarizes the laboratory tests that are recommended in different scenarios of possible GBS infection in neonates.
Scenario | Recommended Diagnostic Evaluation |
Infants with signs of sepsis | Complete diagnostic evaluation (class A, level of evidence II)
|
Infants born to women with chorioamnionitis | Limited diagnostic evaluation (class A, level of evidence II)
|
Well-appearing infants PLUS The mother had no chorioamnionitis and no indication for GBS prophylaxis |
No routine diagnostic testing |
Well-appearing infants PLUS The mother received adequate intrapartum GBS prophylaxis |
No routine diagnostic testing (class B, level of evidence III) |
Well-appearing infants PLUS The mother had an indication for GBS prophylaxis but received no or inadequate prophylaxis PLUS The infant is well-appearing PLUS ≥37 weeks and 0 days' gestational age PLUS The duration of membrane rupture before delivery was <18 hours |
No routine diagnostic testing (class B, level of evidence III) |
Well-appearing infants PLUS Either <37 weeks and 0 days' gestational age OR The duration of membrane rupture before delivery was ≥18 hours |
Limited diagnostic evaluation (class B, level of evidence III)
|