Tricuspid stenosis causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
The most common cause of tricuspid stenosis is rheumatic heart disease. Other causes of tricuspid stenosis include carcinoid syndrome, congenital abnormalities, endocarditis, lupus, and mechanical obstruction by a tumor.[1]
Causes of Tricuspid Stenosis
There are at least 4 conditions that are typically attributed with the obstruction of the nativetricuspid valve.
- Rheumatic tricuspid stenosis:
- Diffuse thickening of the leaflets occur. Fusion of the commissures may or may not occur.
- Chordae tendineae may become thickened and shortened
- As a result of the dense collagen and elastic fibers that make up leaflet tissue, the normal leaflet layers become significantly distorted
- Carcinoid heart disease:
- Fibrous white plaques located on the valvular and mural endocardium are characteristic presentations of carcinoid valve lesions
- Valve leaflets become thick, rigid and smaller in area
- Atrial and ventricular surfaces of the valve structure contain fibrous tissue proliferation
- Congenital tricuspid stenosis:
- More common in infants
- Lesions may present in a number of different ways, either singularly or in any combination of the following:
- Incompletely developed leaflets
- Shortened or malformed chordae
- Small annuli
- Papillary muscles of abnormal size and number
- Infective endocarditis:
- Stenosis may develop as a result of large infected vegetation obstructing the opening of the tricuspid valve
- This condition is uncommon
- Unusual and rare causes:
- Fabry disease
- Giant blood cysts
- Other conditions may mimic tricuspid stenosis, obstructing flow through the valve:
- Supravalvular obstruction from congenital diaphragms
- Intracardiac or extracardiac tumors
- Thrombosis or emboli
- Large endocarditis vegetations
- Other conditions that impair right-sided filling
- Constrictive pericarditis
- Restrictive Cardiomyopathy
References
- ↑ Baumgartner H, Hung J, Bermejo J, Chambers JB, Evangelista A, Griffin BP; et al. (2009). "Echocardiographic assessment of valve stenosis: EAE/ASE recommendations for clinical practice". Eur J Echocardiogr. 10 (1): 1–25. doi:10.1093/ejechocard/jen303. PMID 19065003.