Silicosis classification
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
There are 5 subtypes of silicosis that are differentiated according to the duration of exposure, development of symptoms, pulmonary function, and findings on chest imaging. Silicosis is classified as either simple chronic, complicated chronic, interstitial pulmonary fibrosis, accelerated silicosis, or acute silicosis.
Classification
There are 5 subtypes of silicosis that are differentiated according to the duration of exposure, development of symptoms, pulmonary function, and findings on chest imaging.[1][2][3]
| Subtype | Simple Chronic | Complicated Chronic | Interstitial Pulmonary Fibrosis | Accelerated Silicosis | Acute Silicosis |
| Duration of Exposure | Disease develops > 10 years following exposure to low - moderate concentrations of silica dust | Disease develops > 10 years following exposure to silica dust | Disease develops > 10 years following exposure to silica dust. | Disease develops 5 to 10 years following high exposure to silica dust | Disease develops within 5 years of exposure to extremely high concentrations of silica dust |
| Symptoms | Often asymptomatic | Dyspnea and cough | Dyspnea and cough | Dyspnea, weakness, and weight loss | Severe, disabling dyspnea, weakness, weight loss, and progressive respiratory failure |
| Pulmonary Function | May be either normal or reduced | May be either normal or reduced | May be either normal or reduced | Reduced with rapid deterioration of FVC and FEV1 | Reduced with restrictive changes and reduced diffusion capacity |
| Imaging Findings | Nodules < 10 mm | Nodules > 1 cm with either obstructive or restrictive changes of variable severity | Diffuse reticulonodular pattern similar to idiopathic pulmonary fibrosis | Rapidly progressing nodules and masses | Bilateral perihilar acinar pattern consolidations with ground glass appearance |
References
- ↑ Arakawa H, Johkoh T, Honma K, Saito Y, Fukushima Y, Shida H; et al. (2007). ; "Chronic interstitial pneumonia in silicosis and mix-dust pneumoconiosis: its prevalence and comparison of CT findings with idiopathic pulmonary fibrosis" Check
|url=value (help). Chest. 131 (6): 1870–6. doi:10.1378/chest.06-2553. PMID 17400659. - ↑ Park R, Rice F, Stayner L, Smith R, Gilbert S, Checkoway H (2002). ; "Exposure to crystalline silica, silicosis, and lung disease other than cancer in diatomaceous earth industry workers: a quantitative risk assessment" Check
|url=value (help). Occup Environ Med. 59 (1): 36–43. PMC 1740205. PMID 11836467. - ↑ Greenberg MI, Waksman J, Curtis J (2007). ; "Silicosis: a review" Check
|url=value (help). Dis Mon. 53 (8): 394–416. doi:10.1016/j.disamonth.2007.09.020. PMID 17976433.