Silicosis natural history, complications and prognosis
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Please help WikiDoc by adding content here. It's easy! Click here to learn about editing. complications Tuberculosis: association between silicosis and TB has been known for a long time, but more recent findings show that exposure to silica, without silicosis, may also predispose individuals to TB [1]The increased risk of both pulmonary and extra-pulmonary TB is lifelong even if exposure ceases[2]. the risk increases with severity of silicosis . acute and accelerated silicosis . Pulmonary TB rates can be extremely high in silica-exposed groups with high background population TB and HIV rates. In many instances, it is the chest radiograph rather than clinical features that gives the first indication of TB in the presence of silicosis. Treatment for latent TB infection in people with silicosis (especially those with HIV infection) is recommended.[3] Screening for latent TB , tuberculin skin tests are used to diagnose latent TB, after which a 9-month course of INH is recommended,
References
- ↑ Cowie RL (1994). "The epidemiology of tuberculosis in gold miners with silicosis". Am J Respir Crit Care Med. 150 (5 Pt 1): 1460–2. doi:10.1164/ajrccm.150.5.7952577. PMID 7952577.
- ↑ Hnizdo E, Murray J (1998). "Risk of pulmonary tuberculosis relative to silicosis and exposure to silica dust in South African gold miners". Occup Environ Med. 55 (7): 496–502. PMC 1757613. PMID 9816385.
- ↑ "Adverse effects of crystalline silica exposure. American Thoracic Society Committee of the Scientific Assembly on Environmental and Occupational Health". Am J Respir Crit Care Med. 155 (2): 761–8. 1997. doi:10.1164/ajrccm.155.2.9032226. PMID 9032226.