Tremor causes

Jump to navigation Jump to search

Tremor Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Tremor from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

Echocardiography and Ultrasound

CT

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Tremor causes On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Tremor causes

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Tremor causes

CDC on Tremor causes

Tremor causes in the news

Blogs on Tremor causes

Directions to Hospitals Treating Tremor

Risk calculators and risk factors for Tremor causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Naresh Mullaguri, M.B.B.S. [2] Kiran Singh, M.D. [3]

Overview

Tremor[1] is generally caused by problems in parts of the brain or spinal cord that control muscles throughout the body or in particular areas, such as the hands. Neurological disorders or conditions that can produce tremor include multiple sclerosis, stroke, traumatic brain injury and neurodegenerative diseases that damage or destroy parts of the brainstem or the cerebellum. Other causes include the use of some drugs (such as amphetamines, caffeine, corticosteroids, and drugs used for certain psychiatric disorders), alcohol abuse or withdrawal, mercury poisoning, overactive thyroid or liver failure. Tremors can be an indication of hypoglycemia, along with palpitations, sweating and anxiety. Tremor can also be caused from lack of sleep, vitamins, or having too much stress. Deficiencies of magnesium and vitamin B1 have also been known to cause tremor or shaking which resolves when the deficiency is corrected. See magnesium in biology. Some forms of tremor are inherited and run in families, while others have no known cause. Tremors can also be caused by some spider bites i.e. the redback spider of Australia.

Tremor can result from other conditions as well. Alcoholism, excessive alcohol consumption, or alcohol withdrawal can kill certain nerve cells, resulting a tremor known as asterixis. Conversely, small amounts of alcohol may help to decrease familial and essential tremor, but the mechanism behind this is unknown. Tremor in peripheral neuropathy may occur when the nerves that supply the body’s muscles are traumatized by injury, disease, abnormality in the central nervous system, or as the result of systemic illnesses. Peripheral neuropathy can affect the whole body or certain areas, such as the hands, and may be progressive. Resulting sensory loss may be seen as a tremor or ataxia (inability to coordinate voluntary muscle movement) of the affected limbs and problems with gait and balance. Clinical characteristics may be similar to those seen in patients with essential tremor.

Causes

Life Threatening Causes

Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.

Common Causes

Causes by Organ System

Cardiovascular Cerebrovascular accident,hypothermia,vitamin b1 deficiency
Chemical / poisoning 3-Aminopyridine, 4-aminopyridine, acetylene dichloride, acidic dry cell batteries , acrylamide, agrocide, agronexit, amidithion, amiton, aparasin, aphtiria, arsenic poisoning, athyl-gusathion, azinfos-methyl, azinfosethyl, azinphos, azinphosmetile, azothoate, ben-hex, benoxafos, benzene hexachloride, bexol, biphenyl, bromide, bromoform, bromophos, bromophos-ethyl, bromophos-ethyl , cadusafos, carbamate insecticide poisoning, carbinoxamine, carbon disulfide, carbon disulfide, carbon tetrachloride, carbophenothion, chlordane, chlordane , chlordecone, chloresene, chlorfenvinphos, chlorfenvinphos, chloromethane, chloropyrifos, chlorpyrifos methyl, cresols, cresols , cresylic acid, cyanthoate, D-phenothrin, DDD, DDT, demeton, demeton-methyl, demeton-o, demeton-S-methylsulphon, dialifos, diazinon, diborane, dichlorvos, dichlorvos , dimethoate, dimethoate, dioxathion, diquat dibromide, disulfiram, disulfiram, disulfoton, endosulfan, endothion, epichlorohydrin, ethion, ethoate-methyl, ethoprophos, ethyl mercaptan, ethyl-guthion, ethyl-guthion , ethylbenzene, ethylene dichloride, etrimfos, etrimfos , fenchlorphos, fenitrothion, fensulfothion, fenthion, fipronil, fluoridated toothpaste, fonophos, formothion, gamma-hcch, gasoline, glaze, glufosinate, glycol ether, glycol ether , heptachlor,heptenophos, hexachlorocyclohexane(gamma), Iodofenphos, lead, lindane, lithium, lithium toxicity, lobelia poisoning, malathion, manganese, mecarbam, mercury poisoning, mescal poisoning, metaldehyde, methacrifos, methamidophos, methidathion, methylene chloride, metiltriazotionmevinphos, monocrotophos, monosodium methyl arsenate, nicotine poisoning, omethoate, organophosphate insecticide poisoning, oxydeprofos, oxydisulfoton,parathion methyl, parathion, parathion , phenkapton, phenol, phorate, phosalone, phosalone , phosmet, phosphamidon, phosphamidon , phosphine, phoxim, phoxim , pirimiphos-methyl, primiphos methyl, prothidathion, prothoate, pyrethrin, pyrimitate, quinalphos, quintiofos, RDX, rotenone, sea hare poisoning, selenium poisoning, sophamide, sulfite , sulfotep, sulfuryl fluoride, terbufos, tetrachloroethane, thallium, thallium sulfate, thiometon, tolclofos methyl, toxaphene, triazophos, triazotion, trichloroethylene, trifenfos, tubatoxin poisoning, vamidothion, Xylene
Dermatologic Chediak-Higashi disease


Drug Side Effect Amiodarone, amphetamine, artemether and lumefantrin, black cohosh, butorphanol, cidofovir, clozapine, corticosteroids,caspofungin acetate, cyclosporin, cytomegalovirus immune globulin, Dexedrine overdose, Dimercaprol, disulfiram , dobutamine, dopamine, dopexamine, efavirenz, ephedrine, epinephrine, eslicarbazepine acetate, febuxostat, fluvoxamine, glipizide, glycerol phenylbutyrate,Haloperidol, Isoprenaline, Isoproterenol (aerosol),Ivermectin, Lenalidomide, Levalbuterol, Levodopa, Lidocaine, Lidocaine, Loxapine, Margosa oil, Metaraminol,Methoxamine, Miglustat, Nabilone, Nalmefene, Norepinephrine, Orphenadrine, Oxaprozin, Oxcarbazepine, Paroxetine, Pentamidine Isethionate, Peppermint oil, Phentermine, Phenylephrine, Pilocarpine, Pirbuterol, Ramucirumab, Reproterol, Rifaximin, Rizatriptan, Salbutamol, Sodium oxybate,Sodium valproate, Tacrolimus, Terbutaline, Thalidomide, Thallous Chloride Tl 201, Theophylline , Tricyclic antidepressants, Trifluperidol, Valganciclovir hydrochloride, Valproic acid, Venlafaxine, Vilazodone, Xamoterol
Ear Nose Throat No underlying causes
Endocrine Adrenal adenoma, Adrenal cancer, Adrenal incidentaloma, Adrenal tumor, Diabetes insipidus, Diabetes mellitus, High T4 syndrome, Hyperadrenalism, Hyperthyroidism, Toxic multinodular goiter, Pheochromocytoma, Pituitary tumors
Environmental Minamata disease
Gastroenterologic Cirrhosis of liver
Genetic Chromosome 20p, partial duplication, Friedreich ataxia, Huntington's Disease, Mental retardation X-linked Cabezas type
Hematologic Chediak-Higashi syndrome
Iatrogenic Neuroleptic malignant syndrome, Serotonin Syndrome, Ureterosigmoidostomy
Infectious Disease Central Nervous system protozoal infections like Toxoplasmosis, Sleeping sickness (East african), Sleeping sickness (West african), Meningoencephalitis, Creutzfeldt-Jakob disease , Krabbe leukodystrophy, Neurosyphilis, Ramsay Hunt syndrome
Musculoskeletal / Ortho Amish nemaline myopathy
Neurologic Alcoholic cerebellar degeneration, Alcoholic intoxication, Alzheimer's disease, Amyloidosis, oculoleptomeningeal , Aniridia cerebellar ataxia mental deficiency, Anxiety, Basal ganglia calcification, Benign essential tremor, Bovine spongiform encephalopathy, Brain Fag syndrome, Central nervous system protozoal infections, Cerebellar degeneration, Cerebellar disease, Cerebrovascular accident, Creutzfeldt-Jakob disease, Dementia With Lewy Bodies, Diencephalic syndrome, Drug-induced parkinsonism, Dystonia 1, torsion, autosomal dominant, Dystonia musculorum deformans, Dystonia, Essential tremor, Fatal familial insomnia, Friedreich ataxia, Frontotemporal dementia, Huntington's Disease, Idiopathic dystonia DYT1, Parkinson's disease, Krabbe leukodystrophy, Leukoencephalopathy -- metaphyseal chondrodysplasia, Meningoencephalitis, Mental retardation, X-linked, Cabezas type, Metabolic encephalopathy, Metachromatic leukodystrophy, Multiple sclerosis[2], Multiple system atrophy, Myoclonic epilepsy benign, Neuronal intranuclear inclusion disease, Neurosyphilis, Normokalemic periodic paralysis, Olivopontocerebellar Atrophy, Oppenheim's dystonia, Pallidopyramidal syndrome, Parkinsonism, Pelizaeus-Merzbacher disease, Pick's disease of the brain, Spastic paraparesis deafness, Spinocerebellar ataxia
Nutritional / Metabolic Arginase deficiency, Fucosidosis, Ceroid lipofuscinosis, Holocarboxylase synthetase deficiency, Methylmalonic acidemia with homocystinuria, Motor and cognitive disorder due to sepiapterin reductase deficiency, Mucolipidosis, Purine nucleoside phosphorylase deficiency, Sialidosis, Uraemia, Vitamin B1 deficiency
Obstetric/Gynecologic No underlying causes
Oncologic Adrenal adenoma, Pituitary tumors, Pheochromocytoma, Adrenal incidentaloma
Opthalmologic Optic atrophy
Overdose / Toxicity Dexedrine, Methamphetamine, Lithium toxicity[3]
Psychiatric Hysteria, Anxiety, Psychogenic movement disorders
Pulmonary Respiratory failure
Renal / Electrolyte Hypoglycemia, Hypomagnesemia, Normokalemic periodic paralysis
Rheum / Immune / Allergy No underlying causes
Sexual No underlying causes
Trauma No underlying causes
Urologic No underlying causes
Dental No underlying causes
Miscellaneous Shy-Drager syndrome, Senile, Roussy-Levy syndrome, Salvioli syndrome, Wolfram syndrome, Primary orthostatic tremor[4], Physiologic tremor, Lindsay-Burn syndrome, Lhermitte-McAlpine syndrome, Kennedy's disease, Hypothermia, Da Costa's syndrome, Combarros Calleja Leno syndrome, Cockayne syndrome

Causes in Alphabetical Order

The unnamed parameter 2= is no longer supported. Please see the documentation for {{columns-list}}.
3

References

  1. Zeuner KE, Deuschl G (2012). "An update on tremors". Curr. Opin. Neurol. 25 (4): 475–82. doi:10.1097/WCO.0b013e3283550c7e. PMID 22772877. Unknown parameter |month= ignored (help)
  2. Karmon Y, Morrow SA, Weinstock A, Hojnacki D, Weinstock-Guttman B (2012). "Limb ataxia originating from peri-central sulcus demyelinating lesion in multiple sclerosis". J. Neurol. Sci. 320 (1–2): 136–40. doi:10.1016/j.jns.2012.05.039. PMID 22698481. Unknown parameter |month= ignored (help)
  3. Bogers CH, Boshuisen ML, Kok JS, Knegtering H (2012). "[Neurotoxicity in elderly patients being treated with lithium: is there a reason to adjust the dosage administered?]". Tijdschr Psychiatr (in Dutch; Flemish). 54 (4): 359–69. PMID 22508354.
  4. Virmani T, Louis ED, Waters C, Pullman SL (2012). "Familial orthostatic tremor: an additional report in siblings". Neurology. 79 (3): 288–9. doi:10.1212/WNL.0b013e31825fdfb3. PMID 22764256. Unknown parameter |month= ignored (help)
  5. Chemaly RE, Moussalli AS (2012). "Parkinsonian syndrome as a complication of systemic lupus erythematosus. Report of a case and review of the literature". J Med Liban. 60 (2): 103–5. PMID 22919866.