Nasopharyngeal carcinoma natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Prognosis

The five-year survival rate of nonkeratinizing and undifferentiated nasopharyngeal carcinomas, with appropriate treatment, is about 65% overall. Cure is highly possible, even when disease has spread to the regional lymph nodes. The prognosis of keratinizing NPC is significantly worse, due to its greater resistance to radiation.[1]

Complications

  • Airway obstruction
  • Difficulty swallowing
  • Disfigurement of the neck or face
  • Hardening of the skin of the neck
  • Loss of voice and speaking ability
  • Spread of the cancer to other body areas (metastasis)

References

  1. Richard Cote, Saul Suster, Lawrence Weiss, Noel Weidner (Editor). Modern Surgical Pathology (2 Volume Set). London: W B Saunders. ISBN 0-7216-7253-1.

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