Nasopharyngeal carcinoma other diagnostic studies
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Nasopharyngeal carcinoma Microchapters |
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Differentiating Nasopharyngeal carcinoma from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2]
Overview
Biopsy may be helpful in the diagnosis of nasopharyngeal carcinoma.
Other Diagnostic Studies
Biopsy may be helpful in the diagnosis of nasopharyngeal carcinoma.
Biopsy Findings
Microscopic Features:[1]
- Prominent lymphoid component - key feature
- Features of squamous cell carcinoma:
- Cohesive cells with:
- Abundant dense eosinophilic cytoplasm
- Central nuclei +/- small/indistinct nucleoli
- Cohesive cells with:
Immunohistochemistry
- EBER +ve
- p16 -ve[2]
References
- ↑ Nasopharyngeal carcinoma http://librepathology.org/wiki/index.php/Nasopharyngeal_carcinoma
- ↑ Gulley ML, Nicholls JM, Schneider BG, Amin MB, Ro JY, Geradts J (1998). "Nasopharyngeal carcinomas frequently lack the p16/MTS1 tumor suppressor protein but consistently express the retinoblastoma gene product". Am. J. Pathol. 152 (4): 865–9. PMC 1858242. PMID 9546345. Unknown parameter
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