Gliomatosis cerebri pathophysiology
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Pathophysiology
Pathogenesis
- Gliomatosis cerebri may be classified into primary (de novo) or secondary, with the latter as a result from the spreading of a more focal glioma.
- According to WHO classification of brain tumors, gliomatosis cerebri is classified into grade 2 or grade 3 tumors.
Associated Conditions
Gliomatosis cerebri may be associated with:[1]
Gross Pathology
On gross pathology, gliomatosis cerebri is characterized by:
- Diffuse, usually astrocytic growth pattern
- Involves at least three cerebral lobes
- Bilateral involvement of the cerebral hemispheres, deep gray matter, brainstem, or cerebellum
References
- ↑ Buis DR, van der Valk P, De Witt Hamer PC (2012). "Subcutaneous tumor seeding after biopsy in gliomatosis cerebri". J Neurooncol. 106 (2): 431–5. doi:10.1007/s11060-011-0678-2. PMC 3230756. PMID 21837541.