Hairy cell leukemia risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]

Overview

Studies have proposed a number of risk factors for the development of hairy cell leukmeia such as certain chemicals exposure, radiation exposure, and sawdust exposure.[1]

Risk Factors

  • Studies have proposed a number of risk factors for the development of hairy cell leukmeia include:[1]
  • Chemicals exposure: exposure to either herbicides or diesel may be correlated with an increased risk of hairy cell leukemia.
  • Radiation exposure: excessive X ray imaging or prior radiotherapy may be associated with increased risk of hairy cell leukemia.
  • Sawdust exposure: occupations that involve exposure to sawdust and wood may be associated with increased risk of hairy cell leukemia development.
  • Ethnicity: hairy cell leukemia usually more commonly affects individuals of the Ashkenazi Jewish ancestry males relative to other ethnic groups.
  • Gender: males are more commonly affected with multiple myeloma than females. The male to female ratio is approximately 4 to 1.[2][3]
  • Age: The chance to develop hairy cell leukemia increases as patients get older, where where it is rarely diagnosed in patients younger than 30 years of age.[2][4]

References

  1. 1.0 1.1 Hairy cell leukemia. MAYO CLINIC (2015) http://www.mayoclinic.org/diseases-conditions/hairy-cell-leukemia/basics/risk-factors/con-20026432 Accessed on October, 20 2015
  2. 2.0 2.1 Hairy cell leukaemia risks and causes. Cancer Research UK (2015) http://www.cancerresearchuk.org/about-cancer/type/hairy-cell-leukaemia/about/hairy-cell-leukaemia-risks-and-causes Accessed on October, 21 2015
  3. Epidemiology. HAIRY CELL LEUKEMIA FOUNDATION. (2015) https://www.hairycellleukemia.org/professionals/epidemiology/ Accessed on October, 21 2015
  4. Hairy Cell Leukemia. Wikipedia (2015) https://en.wikipedia.org/wiki/Hairy_cell_leukemia#Pathophysiology Accesed on October, 20 2015


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