Hepatoblastoma natural history
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Hepatoblastoma Microchapters |
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Hepatoblastoma natural history On the Web |
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Risk calculators and risk factors for Hepatoblastoma natural history |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2] Nawal Muazam M.D.[3]
Overview
Natural History
Complications
Paraneoplastic features of hepatoblastoma are not uncommon at presentation and include:[1]
- Erythrocytosis
- Thrombocytosis
- Hypocalcaemia
- Isosexual precocious puberty
- Hypoglycaemia
Prognosis
- The 5-year survival rate of children with hepatoblastoma is approximately 70%.[2]
- The table below lists prognosis of hepatoblastma based on staging:[3]
| Subtype | Description |
|---|---|
| Stage I |
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| Stage II |
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| Stage III |
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| Stage IV |
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Factors that Affect Prognosis (chance of recovery) and Treatment Options
- The 5-year survival rate of children with hepatoblastoma is approximately 70%.
- The prognosis (chance of recovery) and treatment options depend on the following:
- The stage of the cancer (the size of the tumor
- Whether it affects part or all of the liver
- Whether it has spread to other places in the body, such as the lungs).
- Whether the cancer can be removed completely by surgery.
- The type of liver cancer (hepatoblastoma or hepatocellular).
- Whether the cancer has just been diagnosed or has recurred.
- Prognosis may also depend on:
- Certain features of the cancer cell (determined microscopically).
- Whether the AFP blood levels go down after chemotherapy is initiated.
References
- ↑ Madabhavi, Irappa; Patel, Apurva; Choudhary, Mukesh; Aagre, Suhas; Revannasiddaiah, Swaroop; Modi, Gaurang; Anand, Asha; Panchal, Harsha; Parikh, Sonia; Raut, Shreeniwas (2014). "Paraneoplastic Recurrent Hypoglycaemic Seizures: An Initial Presentation of Hepatoblastoma in an Adolescent Male—A Rare Entity". Case Reports in Pediatrics. 2014: 1–5. doi:10.1155/2014/104543. ISSN 2090-6803.
- ↑ Prognosis and Prognostic Factors. National Cancer Institute 2015. http://www.cancer.gov/types/liver/hp/child-liver-treatment-pdq#link/_570_toc. Accessed on October 28, 2015
- ↑ Treatment and prognosis of hepatoblastoma. Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/hepatoblastoma. Accessed on November 3, 2015