Parathyroid cancer diagnostic criteria
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
The diagnosis of parathyroid cancer is made when if any of the following 5 diagnostic criteria are met: Hypercalcemia is greater than 14 milligrams per deciliter, serum parathyroid hormone levels are greater than twice that of normal, a palpable cervical mass in a hypercalcemic patient, unilateral vocal cord paralysis with hypercalcemia, and concomitant renal and skeletal disease observed in a patient with a markedly elevated serum parathyroid hormone.
Diagnostic Criteria
- Parathyroid carcinoma should be suspected clinically if:
- Hypercalcemia is greater than 14 milligrams per deciliter.
- Serum parathyroid hormone levels are greater than twice that of normal.
- A cervical mass is palpated in a hypercalcemic patient.
- Hypercalcemia is associated with unilateral vocal cord paralysis.
- Concomitant renal and skeletal disease are observed in a patient with a markedly elevated serum parathyroid hormone.