Liver mass biopsy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]

Overview

Biopsy for liver mass may be classified into 2 categories: non-surgical biopsy and surgical biopsy. Biopsy findings associated with liver mass will depend on tumor histology. Common types of liver tissue biopsy for liver mass, include: channels lined by benign endothelium, fibromuscular hyperplasia, and loss of reticulin scaffold. Common indications for biopsy in liver mass, include: suspected hepatocellular carcinoma, liver metastases, and unspecific imaging findings. The most important contraindication for biopsy in liver mass is suspected hemangioma.

Biopsy

Biopsy for liver mass may be classified into 2 categories:

• Non-surgical biopsy

• Fine needle biopsy
• Normally used to evaluate some types of liver lesions, such as hepatic adenomas and focal nodular hyperplasia

• Surgical

• Surgical resection

• The preferred biopsy technique for malignant liver mass is surgical resection.

• Indications for biopsy in liver mass, include:

• Contraindications for biopsy in liver mass, include:

• Suspected hemangioma
• High risk of seeding of neoplastic cells
• Intake of anticoagulants
• Unstable medical conditions (eg. acute heart failure)

• Complications for for biopsy in liver mass, include:

• Bleeding
• Seeding of neoplastic cells

Surgical Biopsy

• Surgical excision is the mainstay therapy for malignant liver mass
• Surgical excision is also the primary choice for the definitive diagnosis of malignant liver mass
• In lung mass, surgical procedure selection will depend on the size, margins, and size of the tumor.
• Common surgical procedures for the treatment of liver mass, include: