Guillain-Barré syndrome diagnostic criteria

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editors-In-Chief: Priyamvada Singh, MBBS [2]

Diagnostic Criteria

Required

• Progressive, relatively symmetrical weakness of 2 or more limbs due to neuropathy
• Areflexia
• Disease course < 4 weeks
• Exclusion of other causes (see below)

Supportive

• Relatively symmetric weakness accompanied by numbness and/or tingling
• Mild sensory involvement
• Facial nerve or other cranial nerve involvement
• Absence of fever
• Typical CSF findings obtained from lumbar puncture
• Electrophysiologic evidence of demyelination from electromyogram