Necrotizing fasciitis risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
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Overview
Risk Factors
Common risk factors in the development of necrotizing fasciitis are:
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! Type 1 !! Type 2 !!! Type 3 !!!! Type 4
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| Alcohlism
● Antecedent trauma
● Carcinoma
● Cardiopulmonary disease
● Diabetes
● Iatrogenic procedures
● Immunosupression ( e.g.,HIV and corticosteroid use)
● Intravenous drug abuse
● Male gender
● Peripheral vasular disease
● Recent surgery
● Smoking
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| Type 2 (20% to 30% cases)
Monomicrobial || ● Beta-Hemolytic Streptococci group A (Streptococcus pyogenes)
● with/without Staphylococcus aureus
● Skin or throat derived
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| Type 3 (common in Asia)
Gram negative monomicrobial NF (including marine related organisms)|| ● Vibrio spp mainly
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| Type 4 (Fungal) || ● Candida (Immunocompromised patients)
● Zygomycetes (Immunocompetent patients)
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