Necrotizing fasciitis differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yamuna Kondapally, M.B.B.S[2]

Overview

Necrotizing fasciitis must be differentiated from other diseases that cause erythema, pain, edema and necrosis of soft tissues such as sun burn, cellulitis, erysipelas, diabetic myonecrosis and vasculitis.

Differential Diagnosis

Necrotizing fasciitis must be differentiated from:

Early stage

• Muscle strains
• Viral illness
• Thrombosis
• Sprain or exacerbation of gout
• Sun burn or an allergic rash

Late stage

• Nonnecrotizing fasciitis (eosinophilic fasciitis, para neoplastic fasciitis, nodular fasciitis and proliferative fasciitis)
• Cellulitis
• Dermatomyositis
• Erys
• Vaculitis (Lupus myofasciitis, Churg-strauss vasculitis and others)
• Graft-versus-host disease (GVHD)
• Diabetic myonecrosis
• Compartment syndrome
• Lymphedema
• Phlegmasia cerulea dolens
• Myxedema
• Gastroenteritis