Sickle-cell disease CT
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shyam Patel [2]
Overview
A CT scan be indicated to assess for signs of ischemia or thrombosis in particular organs or tissues.
CT
CT scans can show pathology in patients with sickle cell disease. Most pathology stems from vaso-occlusive crises. For patients who present with neurological deficits or altered mental status, noncontrast CT of the head is the diagnostic test of choice. This is important since it can help rule out infarction or hemorrhage. CT scans of other parts of the body are based on whether a patient has symptoms. Below are representative images from patients with sickle cell disease who have suffered various complications.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172721/bin/nihms-310958-f0001.jpg CT of the orbit in a patient with sickle cell disease. Shown is orbital wall infarction due to vaso-occlusive crisis. There is periorbital soft tissue edema.[1]
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172721/bin/nihms-310958-f0002.jpg CT of the head in a patient with sickle cell disease. Shown is a subarachnoid hemorrhage.[1]
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172721/bin/nihms-310958-f0004.jpg CT of the abdomen in a patient with sickle cell disease. Shown are splenic infarcts.
References
- ↑ 1.0 1.1 Brandow AM, Liem R (2011). ""Sickle Cell Disease in the Emergency Department: Atypical Complications and Management"". Clin Pediatr Emerg Med. 12 (3): 202–212. doi:10.1016/j.cpem.2011.07.003. PMC 3172721. PMID 21927581.