Congenital rubella syndrome primary prevention

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Kalsang Dolma, M.B.B.S.[2]

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Primary Prevention

  • MMR vaccination prior to pregnancy can prevent congenital rubella syndrome.
  • Because rubella spreads from person to person via the respiratory route, pregnant women who are not immune to rubella should avoid contact with persons known to carry the virus.
  • Cases of U.S.-acquired rubella have occurred among susceptible persons providing care for infants with CRS. Because infants can shed the virus for prolonged periods, (up to 1 year of age or longer) infants with CRS should be considered infectious until they are at least 1 year old or until two cultures of clinical specimens obtained one month apart after the infant is older than three months of age are negative for rubella virus. Infants with CRS should be placed in contact isolation during any hospital admission before age one year or until the infant is no longer considered infectious. In addition, health officials should consider excluding infants with CRS from child care facilities until he or she is no longer considered infectious. Persons having contact with infants with CRS should have documented evidence of immunity to rubella and caregivers of infants with CRS should be aware of the potential hazard of the infants to susceptible pregnant contacts.

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