Amoebic liver abscess history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Yamuna Kondapally, M.B.B.S[2]

Overview

History

  • History of recent travel to or resident of endemic areas.
  • Time of onset (duration of symptoms <14 days)
  • History of fever and abdominal pain

Symptoms

After exposure, 80% of infected patients develop symptoms with in few days to 4-5 weeks. Symptoms of amoebic liver abscess include:[1][2][3][4][5]

  • Moderate to severe abdominal pain (localized to right upper quadrant radiated to right shoulder or diffuse and pain is intense, continuous or stabbing)
  • Malaise (uneasiness, or ill feeling)
  • Loss of appetite
  • Sweating
  • Weight loss
  • Epigastric pain (Commonly seen in left lobe abscesses)
  • Fever (high fever with chills is suggestive of secondary bacterial infection)
  • Anorexia
  • Pleuritic chest pain
  • Cough with or without expectoration
  • Yellow discoloration of skin (Jaundice is seen in 1/3 of patients)
  • Confusion (due to encephalopathy)
  • Abdominal distension (due to ascites)
  • Nausea and vomiting
  • Diarrhea
  • Constipation

References

  1. Ximénez C, Morán P, Rojas L, Valadez A, Gómez A, Ramiro M; et al. (2011). "Novelties on amoebiasis: a neglected tropical disease". J Glob Infect Dis. 3 (2): 166–74. doi:10.4103/0974-777X.81695. PMC 3125031. PMID 21731305.
  2. Ximénez C, Morán P, Rojas L, Valadez A, Gómez A (2009). "Reassessment of the epidemiology of amebiasis: state of the art". Infect Genet Evol. 9 (6): 1023–32. doi:10.1016/j.meegid.2009.06.008. PMID 19540361.
  3. Pritt BS, Clark CG (2008). "Amebiasis". Mayo Clin Proc. 83 (10): 1154–9, quiz 1159-60. doi:10.4065/83.10.1154. PMID 18828976.
  4. Ali IK, Solaymani-Mohammadi S, Akhter J, Roy S, Gorrini C, Calderaro A; et al. (2008). "Tissue invasion by Entamoeba histolytica: evidence of genetic selection and/or DNA reorganization events in organ tropism". PLoS Negl Trop Dis. 2 (4): e219. doi:10.1371/journal.pntd.0000219. PMC 2274956. PMID 18398490.
  5. Ximénez C, Cerritos R, Rojas L, Dolabella S, Morán P, Shibayama M; et al. (2010). "Human amebiasis: breaking the paradigm?". Int J Environ Res Public Health. 7 (3): 1105–20. doi:10.3390/ijerph7031105. PMC 2872301. PMID 20617021.